Obstinate cough as a sole presenting symptom of non-metastatic renal cell carcinoma

Int J Urol. 2007 Sep;14(9):854-5. doi: 10.1111/j.1442-2042.2007.01832.x.


Renal cell carcinoma (RCC) causes many kinds of symptoms such as hypercalcemia, hypertension, polycythemia and fever. Here we describe a rare case of RCC presenting with a persistent cough. After radical nephrectomy, the obstinate cough disappeared. When the tumor recurred locally, the cough also recurred. Furthermore, the cough disappeared completely again after the removal of the recurrent tumor. Although all the clinical findings suggested that the RCC caused the cough, we could not identify a specific humoral substance responsible for the cough.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Renal Cell / complications*
  • Cough / etiology*
  • Female
  • Humans
  • Kidney Neoplasms / complications*
  • Middle Aged
  • Neoplasm Recurrence, Local / complications*
  • Paraneoplastic Syndromes / etiology*