Management of posterior uveal melanoma

Surv Ophthalmol. 1991 Nov-Dec;36(3):161-95. doi: 10.1016/0039-6257(91)90001-v.


In recent years, there have been a number of advances in the diagnosis and management of patients with malignant melanoma of the posterior uvea (ciliary body and choroid). This review provides a brief update on the current status of diagnostic modalities, such as fluorescein angiography, ultrasonography, computed tomography, magnetic resonance imaging, fine needle aspiration biopsy, and the radioactive phosphorus uptake test. Following that is a more detailed review of the current controversy regarding the natural course of uveal melanomas and the available therapeutic modalities. Current indications, techniques, complications, and results are provided for various forms of management, such as observation, laser photocoagulation, plaque radiotherapy, charged particle radiotherapy, local tumor resection, enucleation, and orbital exenteration.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Brachytherapy
  • Choroid Neoplasms / diagnosis*
  • Choroid Neoplasms / secondary
  • Choroid Neoplasms / therapy
  • Ciliary Body*
  • Eye Enucleation
  • Fluorescein Angiography
  • Fundus Oculi
  • Humans
  • Light Coagulation
  • Magnetic Resonance Imaging
  • Melanoma / diagnosis*
  • Melanoma / secondary
  • Melanoma / therapy
  • Tomography, X-Ray Computed
  • Uveal Neoplasms / diagnosis*
  • Uveal Neoplasms / secondary
  • Uveal Neoplasms / therapy