Effects of refraction and axial length on childhood optic disk parameters measured by optical coherence tomography

Am J Ophthalmol. 2007 Sep;144(3):459-61. doi: 10.1016/j.ajo.2007.05.010.


Purpose: To assess the effects of refraction and axial length on optical coherence tomography (OCT) measures of childhood optic disk parameters.

Design: Population-based cross-sectional study.

Methods: Of 4,118 children examined in the Sydney Myopia Study (Sydney Childhood Eye Study) from 34 randomly selected primary schools and 21 secondary schools from 2003 through 2005, 3,529 (85.7%) were included in the analysis (1,395 6-year-old children [year 1 students] and 2,134 12-year-old children [year 7 students]). Comprehensive standardized eye examinations included best-corrected visual acuity, cycloplegic autorefraction, biometry measurements, and fast optic disk scans using OCT.

Results: After adjusting for magnification, the mean optic disk area was positively associated with axial length (P(trend) < .0001, both age groups) but was not associated consistently with spherical equivalent refraction (SER).

Conclusions: Optic disk parameters in childhood are influenced by axial length, but not by refractive error itself.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biometry
  • Body Weights and Measures
  • Child
  • Cross-Sectional Studies
  • Eye / anatomy & histology*
  • Female
  • Humans
  • Hyperopia / pathology
  • Male
  • Myopia / pathology
  • Optic Disk / anatomy & histology*
  • Refraction, Ocular / physiology*
  • Tomography, Optical Coherence / methods*
  • Visual Acuity