A few studies indicate that race- and culture-related differences exist among patients with bone tumors. However, there is little information regarding sarcomas. Existing studies indicate that, in the United States, race and cultural background may not significantly affect the survival rate of patients with sarcoma. As we learn more, however, orthopaedic oncologists should look to areas of oncology in which race-based disparity has been reported-specifically, among patients with prostate or breast cancer. These patient populations have been more widely studied, and physicians have pinpointed measures to reduce or eliminate gaps in patient care and prognosis. In particular, oncologists have called for culture-specific patient education. Further research is required to identify disparities, if any, and to ensure equitable patient prognoses.