Acceptability of hypothetical microbicides among women in sex establishments in rural areas in Southern China

Sex Transm Dis. 2008 Jan;35(1):102-10. doi: 10.1097/OLQ.0b013e31814b8546.


Objectives and goal: The objectives of this study were to measure the potential acceptability of a hypothetical microbicide among women in sex establishments in rural areas of Southern China and demographic, behavioral, and social context factors likely to affect microbicide acceptability.

Study design: This was a cross-sectional survey, using a quota sampling, among 300 women from sex establishments in 3 rural towns. An interviewer-administered standardized questionnaire was used to measure the acceptability score of hypothetical microbicides' characteristics, as well as sexual relationships and behaviors and other contextual factors.

Results: Findings showed a generally positive response to microbicides, indicated by an acceptability index score of 2.89 (SD, 0.56, scale of 1-4) in the overall sample. Multivariate analysis shows that the acceptability score varied significantly by study sites, type of sex-work establishments, marital status, sex partner type, vaginal product experience, locus of control by partners, and locus of control by chance.

Conclusions: Microbicides may be acceptable among sex workers in rural settings in China; however, contextual factors should be carefully considered in education and promotion of microbicides in the future.

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Administration, Intravaginal
  • Adolescent
  • Adult
  • Anti-Infective Agents / administration & dosage*
  • China / epidemiology
  • Condoms, Female
  • Cross-Sectional Studies
  • Female
  • Humans
  • Patient Acceptance of Health Care*
  • Rural Health Services
  • Sex Work*
  • Sexually Transmitted Diseases / epidemiology*
  • Sexually Transmitted Diseases / etiology
  • Sexually Transmitted Diseases / prevention & control*
  • Surveys and Questionnaires


  • Anti-Infective Agents