Abstract
Concordance with growth hormone (GH) therapy in 75 children was objectively assessed using data on GP prescriptions over 12 months. 23% missed >2 injections/week. Lower concordance was associated with longer duration on GH therapy (p<0.005), lack of choice of delivery device (p<0.005) and short prescription durations (p<0.005), and predicted lower height velocities (p<0.05).
MeSH terms
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Adolescent
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Body Height / drug effects
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Child
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Cross-Sectional Studies
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Drug Administration Schedule
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Drug Monitoring / methods
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Drug Prescriptions / statistics & numerical data
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Female
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Growth Disorders / drug therapy*
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Growth Disorders / physiopathology
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Human Growth Hormone / administration & dosage*
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Human Growth Hormone / therapeutic use
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Humans
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Longitudinal Studies
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Male
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Patient Compliance*
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Recombinant Proteins / administration & dosage
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Recombinant Proteins / therapeutic use
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Treatment Outcome
Substances
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Recombinant Proteins
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Human Growth Hormone