Primary hypothyroidism with precocious puberty and bilateral cystic ovaries

Indian J Pediatr. 2007 Aug;74(8):781-3. doi: 10.1007/s12098-007-0140-9.


It is a general observation that children with hypothyroidism have delayed sexual maturation and delayed puberty. However, longstanding untreated hypothyroidism could be associated with isosexual precocious puberty. Here we report a nine year old girl with longstanding untreated hypothyroidism presenting with precocious puberty and bilateral multicystic ovaries, which promptly responded to thyroid hormone replacement.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Hypothyroidism / complications
  • Hypothyroidism / diagnosis*
  • Hypothyroidism / therapy
  • Ovarian Cysts / diagnosis*
  • Ovarian Cysts / etiology
  • Ovarian Cysts / therapy
  • Puberty, Precocious / diagnosis*
  • Puberty, Precocious / etiology
  • Puberty, Precocious / therapy