Serum uric acid is significantly related to the components of the metabolic syndrome in Japanese workingmen

J Cardiometab Syndr. 2007 Summer;2(3):158-62. doi: 10.1111/j.1559-4564.2007.06596.x.


The aim of this study was to examine whether serum uric acid (SUA) concentration was related to the metabolic syndrome (MS). A total of 981 Japanese workingmen were studied. MS was diagnosed based on the modified criteria of the International Diabetes Federation. MS was present in 8.0% of the target participants. Logistic regression analysis using a cutoff value of the SUA of 7.0 mg/dL showed that some components of MS and the logarithmic value of the serum C-reactive protein were associated with a significant odds ratio for predicting elevated SUA. The odds ratios and 95% confidence intervals (CIs) of a high logarithmic value of the serum C-reactive protein, large waist girth, elevated blood pressure, and dyslipidemia for elevated SUA were 1.76 (CI, 1.21-2.55), 1.72 (CI, 1.21-2.45), 1.42 (CI, 1.01-2.00), and 1.87 (CI, 1.30-2.69), respectively. Most of the components of MS were significant determinants of SUA.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Biomarkers / blood
  • Blood Glucose
  • C-Reactive Protein / metabolism
  • Cross-Sectional Studies
  • Dyslipidemias / blood*
  • Employment
  • Humans
  • Hypertension / blood*
  • Japan
  • Logistic Models
  • Male
  • Metabolic Syndrome / blood*
  • Middle Aged
  • Obesity / blood*
  • Obesity / epidemiology
  • Risk Factors
  • Surveys and Questionnaires
  • Uric Acid / blood*


  • Biomarkers
  • Blood Glucose
  • Uric Acid
  • C-Reactive Protein