Studies of the McGurk effect have shown that when discrepant phonetic information is delivered to the auditory and visual modalities, the information is combined into a new percept not originally presented to either modality. In typical experiments, the auditory and visual speech signals are generated by the same talker. The present experiment examined whether a discrepancy in the gender of the talker between the auditory and visual signals would influence the magnitude of the McGurk effect. A male talker's voice was dubbed onto a videotape containing a female talker's face, and vice versa. The gender-incongruent videotapes were compared with gender-congruent videotapes, in which a male talker's voice was dubbed onto a male face and a female talker's voice was dubbed onto a female face. Even though there was a clear incompatibility in talker characteristics between the auditory and visual signals on the incongruent videotapes, the resulting magnitude of the McGurk effect was not significantly different for the incongruent as opposed to the congruent videotapes. The results indicate that the mechanism for integrating speech information from the auditory and the visual modalities is not disrupted by a gender incompatibility even when it is perceptually apparent. The findings are compatible with the theoretical notion that information about voice characteristics of the talker is extracted and used to normalize the speech signal at an early stage of phonetic processing, prior to the integration of the auditory and the visual information.