Establishment and characterization of a novel megakaryoblastic cell line, MOLM-1, from a patient with chronic myelogenous leukemia

Y Matsuo; T Adachi; T Tsubota; J Imanishi; J Minowada

Establishment and characterization of a novel megakaryoblastic cell line, MOLM-1, from a patient with chronic myelogenous leukemia

Hum Cell. 1991 Sep;4(3):261-4.

Authors

Y Matsuo¹, T Adachi, T Tsubota, J Imanishi, J Minowada

Affiliation

¹ Department of Internal Medicine, Okayama City Hospital.

PMID: 1782185

Abstract

Based on the morphological resemblance to megakaryocytes and upon the expression f the platelet specific glycoprotein antigen, CD61, it is highly l y that MOLM-1 is a clonal leukemic cell population of megakaryoblastic origin .

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Antigens, CD / analysis
Cell Division
Humans
Karyotyping
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / genetics
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology*
Male
Megakaryocytes
Tumor Cells, Cultured

Substances

Antigens, CD