Clinical applications of rhBMP-2 in maxillofacial surgery

Alan S Herford; Philip J Boyne; Roland P Williams

Clinical applications of rhBMP-2 in maxillofacial surgery

J Calif Dent Assoc. 2007 May;35(5):335-41.

Authors

Alan S Herford¹, Philip J Boyne, Roland P Williams

Affiliation

¹ Department of Oral and Maxillofacial Surgery, Loma Linda University School of Dentistry, Loma Linda, CA 92350, USA.

PMID: 17822159

Abstract

Materials and methods: Examples of defects including mandibular continuity defects, preprosthetic atrophic alveolar ridge deficiencies, traumatic defects, and maxillary clefts were included.

Results: All patients demonstrated osseous regeneration stimulated by rhBMP-2.

Conclusion: rhBMP-2 is successful in regenerating bone in a variety of maxillofacial defects. In the future, rhBMP-2 will play a significant role in the treatment of bone deficiencies.

Publication types

Case Reports

MeSH terms

Adolescent
Alveolar Ridge Augmentation / methods
Bone Morphogenetic Protein 2
Bone Morphogenetic Proteins / therapeutic use*
Bone Regeneration / drug effects*
Bone Transplantation / methods
Child
Cleft Palate / surgery
Female
Humans
Male
Mandibular Neoplasms / surgery
Maxilla / surgery
Maxillofacial Injuries / surgery
Middle Aged
Oral Surgical Procedures*
Plastic Surgery Procedures
Recombinant Proteins / therapeutic use*
Transforming Growth Factor beta / therapeutic use*
Wounds, Gunshot / surgery

Substances

Bone Morphogenetic Protein 2
Bone Morphogenetic Proteins
Recombinant Proteins
Transforming Growth Factor beta
recombinant human bone morphogenetic protein-2