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, 370 (9592), 1089-100

The Cardiovascular Toll of Stress


The Cardiovascular Toll of Stress

Daniel J Brotman et al. Lancet.

Erratum in

  • Lancet. 2007 Dec 1;370(9602):1828


Psychological stress elicits measurable changes in sympathetic-parasympathetic balance and the tone of the hypothalamic-pituitary-adrenal axis, which might negatively affect the cardiovascular system both acutely-by precipitating myocardial infarction, left-ventricular dysfunction, or dysrhythmia; and chronically-by accelerating the atherosclerotic process. We provide an overview of the association between stress and cardiovascular morbidity, discuss the mechanisms for this association, and address possible therapeutic implications.

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