Failure of oral zinc supplementation in atopic eczema

Eur J Clin Nutr. 1991 Oct;45(10):507-10.

Abstract

An eight week double-blind placebo-controlled trial of oral zinc sulphate 185.4 mg per day was undertaken in 50 children with atopic eczema aged 1-16 years. In those receiving zinc there was no significant improvement in disease severity as assessed by surface area affected and degree of erythema, symptom scores of itch, sleep disturbance and redness of skin, or weight of emollient or topical steroid use.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Oral
  • Administration, Topical
  • Adolescent
  • Child
  • Child, Preschool
  • Dermatitis, Atopic / drug therapy*
  • Dermatitis, Atopic / pathology
  • Dermatitis, Atopic / physiopathology
  • Double-Blind Method
  • Humans
  • Infant
  • Steroids / administration & dosage
  • Steroids / therapeutic use
  • Sulfates / administration & dosage
  • Sulfates / therapeutic use*
  • Zinc / administration & dosage
  • Zinc / therapeutic use*
  • Zinc Sulfate

Substances

  • Steroids
  • Sulfates
  • Zinc Sulfate
  • Zinc