Identification of DNA in the core component of avian myeloblastosis virus

Biochim Biophys Acta. 1976 May 19;432(3):281-91. doi: 10.1016/0005-2787(76)90137-4.

Abstract

Avian myeloblastosis virus (AMV) was found to contain DNA associated with the virion. The viral envelope was removed by treating the virus with a nonionic detergent and the DNA was found in the core fraction. These experiments indicate that the DNA associated with tumor virus is not contaminant associated with the viral envelope and suggest that the DNA is part of the internal core component. The DNA from avian myeloblastosis virus has a density of 1.70 g/cm3.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Avian Leukosis Virus / analysis*
  • Avian Myeloblastosis Virus / analysis*
  • Avian Myeloblastosis Virus / enzymology
  • Avian Myeloblastosis Virus / ultrastructure
  • Binding Sites
  • Centrifugation, Density Gradient
  • DNA Nucleotidyltransferases / metabolism
  • DNA, Viral* / analysis
  • Microscopy, Electron
  • Molecular Weight
  • Protein Binding
  • Viral Proteins

Substances

  • DNA, Viral
  • Viral Proteins
  • DNA Nucleotidyltransferases