Isotretinoin-induced agranulocytosis

Pediatr Dermatol. Jul-Aug 2007;24(4):425-6. doi: 10.1111/j.1525-1470.2007.00468.x.


Isotretinoin is used to treat a spectrum of dermatologic conditions. The present article reports the case of a 15-year-old female patient who exhibited agranulocytosis after the initiation of isotretinoin administration. Agranulocytosis is a rare but life-threatening side effect of isotretinoin use, and clinicians must be aware of agranulocytosis.

Publication types

  • Case Reports

MeSH terms

  • Acne Vulgaris / drug therapy
  • Adolescent
  • Agranulocytosis / chemically induced*
  • Female
  • Humans
  • Isotretinoin / adverse effects*


  • Isotretinoin