[Transient osteoporosis of the hip in pregnancy. Successful treatment with calcitonin: a case report]

Z Rheumatol. 2007 Oct;66(6):510-3. doi: 10.1007/s00393-007-0191-3.
[Article in German]

Abstract

Transient osteoporosis of the hip is a rare clinical disorder of unknown etiology, characterized by hip pain and functional disability that resolves spontaneously in 6-24 months. Despite a benign prognosis, the long clinical course causes prolonged disability. We report on a case of transient osteoporosis of the hip during pregnancy that was rapidly resolved with the use of calcitonin. An accurate diagnosis was made 2 months after the onset of symptoms (4 weeks postpartum) based on findings in the form of bone marrow edema of the right hip by magnetic resonance imaging. The patient received calcitonin for 8 weeks and the beneficial effect was observed after 3 weeks of therapy with full resolution of symptoms after 8 weeks of therapy (4 months after onset of symptoms). We suggest that the use of calcitonin may be considered as a therapeutic intervention to shorten the disease duration.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Bone Density Conservation Agents / therapeutic use*
  • Calcitonin / therapeutic use*
  • Calcium / therapeutic use
  • Cholecalciferol / therapeutic use
  • Diphosphonates
  • Drug Therapy, Combination
  • Female
  • Hip Joint* / drug effects
  • Hip Joint* / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Organotechnetium Compounds
  • Osteoporosis / diagnosis
  • Osteoporosis / drug therapy*
  • Pregnancy
  • Pregnancy Complications / diagnosis
  • Pregnancy Complications / drug therapy*
  • Pregnancy Trimester, Third
  • Puerperal Disorders / diagnosis
  • Puerperal Disorders / drug therapy
  • Radionuclide Imaging

Substances

  • Bone Density Conservation Agents
  • Diphosphonates
  • Organotechnetium Compounds
  • technetium Tc 99m 1,1-diphosphonopropane-2,3-dicarboxylic acid
  • Cholecalciferol
  • salmon calcitonin
  • Calcitonin
  • Calcium