Simple and sensitive aptamer-based colorimetric sensing of protein using unmodified gold nanoparticle probes

Chem Commun (Camb). 2007 Sep 28:(36):3735-7. doi: 10.1039/b707642h. Epub 2007 Jun 29.

Abstract

We describe herein simple and sensitive aptamer-based colorimetric sensing of protein (alpha-thrombin in this work) using unmodified gold nanoparticle probes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aptamers, Nucleotide / chemistry*
  • Biosensing Techniques / methods*
  • Colorimetry / methods*
  • Gold / chemistry*
  • Metal Nanoparticles / chemistry*
  • Nanotechnology / methods*
  • Thrombin / analysis*

Substances

  • Aptamers, Nucleotide
  • Gold
  • Thrombin