Multiple sclerosis findings in the spinal cord

Expert Rev Neurother. 2007 Sep;7(9):1203-11. doi: 10.1586/14737175.7.9.1203.

Abstract

The spinal cord is commonly affected by acute demyelinating lesions, chronic tissue loss and atrophy in multiple sclerosis, and is a clinically eloquent site. Historically, however, more attention has been focussed on the analysis and contribution of brain lesions. In this review, we discuss some of the key findings from MRI analysis and histopathological examination of the spinal cord, and how they relate to the clinical characteristics of this common and disabling disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Humans
  • Multiple Sclerosis / pathology*
  • Neural Pathways / pathology*
  • Spinal Cord / pathology*