Gastrointestinal eosinophilia

Immunol Allergy Clin North Am. 2007 Aug;27(3):443-55. doi: 10.1016/j.iac.2007.06.002.


Gastrointestinal eosinophilia, a broad term for abnormal eosinophil accumulation in the gastrointestinal tract, involves many different disease identities. These diseases include primary eosinophil associated gastrointestinal diseases, gastrointestinal eosinophilia in hypereosinophilic syndrome, and all gastrointestinal eosinophilic states associated with known causes. Each of these diseases has its unique features but there is no absolute boundary between them. All three groups of gastrointestinal eosinophila are described in this article, although the focus is on primary gastrointestinal eosinophilia.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cytokines / metabolism*
  • Eosinophilia* / diagnosis
  • Eosinophilia* / immunology
  • Eosinophilia* / physiopathology
  • Eosinophilia* / therapy
  • Eosinophils / physiology
  • Gastrointestinal Diseases* / diagnosis
  • Gastrointestinal Diseases* / immunology
  • Gastrointestinal Diseases* / physiopathology
  • Gastrointestinal Diseases* / therapy
  • Humans
  • Hypereosinophilic Syndrome* / diagnosis
  • Hypereosinophilic Syndrome* / physiopathology
  • Hypereosinophilic Syndrome* / therapy


  • Cytokines