Abstract
S-aminopropylcysteine and S-aminoethylhomocysteine are oxidized by snake venom L-amino acid oxidase in the presence of catalase with formation of the respective ketoderivatives. Only the ketoderivative of S-aminopropylcysteine cyclizes to give a seven membered ring (ketimine) absorbing at 296 nm. In the absence of catalase both ketoderivatives are oxidatively decarboxylated.
MeSH terms
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Amines / metabolism
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Amino Acid Oxidoreductases / metabolism*
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Animals
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Catalase / metabolism
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Cysteine / analogs & derivatives*
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Cysteine / metabolism
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Deamination
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Homocysteine / analogs & derivatives*
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Homocysteine / metabolism
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Ketones / metabolism
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L-Amino Acid Oxidase
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Oxidation-Reduction
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Snake Venoms / enzymology*
Substances
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Amines
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Ketones
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Snake Venoms
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Homocysteine
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aminopropylcysteine
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5-(2-aminoethyl)homocysteine
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Catalase
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Amino Acid Oxidoreductases
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L-Amino Acid Oxidase
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Cysteine