Methodological considerations for research in nocturnal home hemodialysis

J Nephrol. Jul-Aug 2007;20(4):381-7.


Nocturnal hemodialysis (NHD) is a form of frequent, intensive renal replacement therapy, which has been suggested to offer multiple physiological benefits over conventional hemodialysis (CHD). Though the evidence supporting these advantages is steadily increasing, significant methodological challenges exist in conducting research in this area. Our review highlights these important considerations and potential biases within the present NHD literature and suggests future research opportunities.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cohort Studies
  • Hemodialysis, Home*
  • Humans
  • Randomized Controlled Trials as Topic / methods*
  • Research