Contrast-enhanced ultrasound for diagnosis of prostate cancer and kidney lesions

Eur J Radiol. 2007 Nov;64(2):231-8. doi: 10.1016/j.ejrad.2007.07.027. Epub 2007 Sep 18.


Purpose of review: Conventional ultrasonography of both, kidney and prostate, is limited due to the poor contrast of B-mode imaging for parenchymal disease and limited sensitivity of colour Doppler for the detection of capillaries and deep pedicular vessels. Contrast-enhanced ultrasound (CEUS) overcomes these limitations.

Recent findings: CEUS investigates the blood flow of the prostate, allows for prostate cancer visualization and for targeted biopsies. Comparisons between systematic and CEUS-targeted biopsies have shown that the targeted approach detects more cancers with a lower number of biopsy cores and with higher Gleason scores compared with the systematic approach. Also the kidney offers promising applications as CEUS improves the detection of abnormal microvascular and macrovascular disorders.

Summary: In recent literature CEUS has shown its value for diagnosis of both, prostate cancer and kidney lesions. This paper describes recent improvements and future perspectives of CEUS.

Publication types

  • Review

MeSH terms

  • Biopsy
  • Contrast Media*
  • Humans
  • Image Enhancement / methods*
  • Kidney / blood supply
  • Kidney / diagnostic imaging
  • Kidney Diseases / diagnostic imaging*
  • Male
  • Prostate / blood supply
  • Prostate / diagnostic imaging
  • Prostatic Neoplasms / diagnostic imaging*
  • Ultrasonography, Doppler
  • Ultrasonography, Interventional


  • Contrast Media