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. 2007 Aug;8(4):425-35.
doi: 10.1089/sur.2006.043.

Single-institutional Experience With the Surgical Infection Prevention Project in Intra-Abdominal Surgery


Single-institutional Experience With the Surgical Infection Prevention Project in Intra-Abdominal Surgery

Traci L Hedrick et al. Surg Infect (Larchmt). .


Background: The incidence of surgical site infection (SSI) is becoming a key component of standard measures of quality of performance. We hypothesized that institutional implementation of a protocol targeting known risk factors would reduce the incidence of SSI associated with intra-abdominal surgery.

Methods: Beginning in June 2004, a quality control initiative was implemented to prevent SSI in patients undergoing intra-abdominal surgical procedures at an academic medical center. This protocol included administration of the proper prophylactic antibiotic 0-60 minutes before incision, continued antibiotic administration for <or=24 hours, and maintenance of intraoperative normothermia (>or=36 degrees C), along with good glycemic control (goal<200 mg/dL 48 h postoperatively) in diabetic patients. Baseline data collected during the initial four months of protocol development (379 patients) were compared with data collected during the last four months of the 11-month study period (390 patients).

Results: Compliance with antibiotic selection increased from 89 percent to 97 percent (p <or= 0.05). Compliance with timeliness of administration improved from 89 percent to 97 percent (p <or= 0.05), whereas cessation of perioperative antibiotics within 24 hours remained constant at 93 and 92 percent, respectively. The incidence of hypothermia fell from 15 percent to 10 percent (p = 0.27). The 30-day incidence of SSI improved from 9.2 percent to 5.6 percent (p = 0.07).

Conclusion: The implementation of a prevention protocol resulted in a substantial trend toward a reduction in the incidence of SSI. These data support the use of protocol implementation as a cost-effective method of reducing perioperative infectious morbidity associated with intra-abdominal surgery.

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