Avoidance of misinterpretation of an FDG positive sacral insufficiency fracture using PET/CT scans in a patient with endometrial cancer: a case report

Clin Nucl Med. 2007 Oct;32(10):779-81. doi: 10.1097/RLU.0b013e318148b408.


Whole-body FDG PET is an important tool for imaging of cancer, including skeletal metastases. However, false-positive results can occur in benign diseases such as insufficiency fractures. We report a case of sacral insufficiency fracture in which increased FDG uptake was detected. Correlative CT images obtained by a combined PET/CT scanner excluded a possible false-positive interpretation by revealing the fracture lines at the site of increased FDG uptake.

Publication types

  • Case Reports

MeSH terms

  • Bone Neoplasms / diagnosis
  • Bone Neoplasms / secondary*
  • Carcinoma / diagnosis
  • Carcinoma / secondary*
  • Diagnosis, Differential
  • Diagnostic Errors / prevention & control*
  • False Positive Reactions
  • Female
  • Fluorodeoxyglucose F18*
  • Fractures, Spontaneous / diagnosis*
  • Fractures, Stress / diagnosis*
  • Humans
  • Image Enhancement / methods
  • Middle Aged
  • Positron-Emission Tomography / methods
  • Radiopharmaceuticals
  • Sacrum / diagnostic imaging
  • Sacrum / injuries*
  • Subtraction Technique
  • Tomography, X-Ray Computed / methods
  • Whole Body Imaging / methods


  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18