Sodium-bicarbonated mineral water decreases aldosterone levels without affecting urinary excretion of bone minerals

Int J Food Sci Nutr. 2008 Jun;59(4):347-55. doi: 10.1080/09637480701560308.

Abstract

AIM To assess in healthy postmenopausal women the influence of consuming sodium-bicarbonated mineral water on postprandial evolution of serum aldosterone and urinary electrolyte excretion.

Methods: Eighteen postmenopausal women consumed 500 ml of two sodium-bicarbonated mineral waters (sodium-bicarbonated mineral water 1 and sodium-bicarbonated mineral water 2) and a low-mineral water with a standard meal. Postprandial blood samples were taken at 60, 120, 240, 360 and 420 min and aldosterone concentrations were measured. Postprandial urinary minerals were determined.

Results: Urinary and total mineral excretion and urinary mineral concentrations did not differ except for sodium concentration, which was significantly higher with sodium-bicarbonated mineral water 1 than with low-mineral water (P = 0.005). There was a time effect (P = 0.003) on the aldosterone concentration. At 120 min, aldosterone concentrations were lower with sodium-bicarbonated mineral water 1 (P = 0.021) and sodium-bicarbonated mineral water 2 (P = 0.030) compared with low-mineral water.

Conclusion: Drinking a sodium-rich bicarbonated mineral water with a meal increases urinary sodium concentration excretion without changes in the excretion of potassium and bone minerals.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldosterone / blood*
  • Analysis of Variance
  • Biomarkers / urine
  • Calcium / urine
  • Chlorides / urine
  • Cross-Over Studies
  • Eating
  • Female
  • Humans
  • Magnesium / urine
  • Middle Aged
  • Mineral Waters*
  • Minerals / urine*
  • Phosphorus / urine
  • Postmenopause / metabolism*
  • Postprandial Period
  • Potassium / urine
  • Sodium / urine
  • Sodium Bicarbonate / administration & dosage*

Substances

  • Biomarkers
  • Chlorides
  • Mineral Waters
  • Minerals
  • Phosphorus
  • Aldosterone
  • Sodium Bicarbonate
  • Sodium
  • Magnesium
  • Potassium
  • Calcium