The alternative complex III from Rhodothermus marinus - a prototype of a new family of quinol:electron acceptor oxidoreductases

FEBS Lett. 2007 Oct 16;581(25):4831-5. doi: 10.1016/j.febslet.2007.09.008. Epub 2007 Sep 14.

Abstract

The biochemical and genetic search for a bc(1) complex in Rhodothermus marinus was always fruitless; however, a functional equivalent, i.e. having quinol:cytochrome c oxidoreductase activity was characterized. Now, with the sequencing of R. marinus genome, it was possible to assign the N-terminal sequences of several proteins of this complex to its coding genes. The alternative complex III from R. marinus has the same genomic organization of the so-called MFIcc complexes, proposed to be oxidoreductases of the respiratory and photosynthetic electron transfer chains. In this report, we establish undoubtedly the existence of an alternative complex III, a functional substitute of the bc(1) complex, by its identification at both the biochemical and genomic level.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins / chemistry*
  • Bacterial Proteins / genetics
  • Electron Transport Complex III / chemistry*
  • Electron Transport Complex III / classification
  • Electron Transport Complex III / genetics
  • Molecular Sequence Data
  • Multigene Family
  • Protein Subunits / chemistry
  • Protein Subunits / genetics
  • Rhodothermus / enzymology*

Substances

  • Bacterial Proteins
  • Protein Subunits
  • Electron Transport Complex III