Sebaceous adenoma of the bulbar conjunctiva in association with glioblastoma multiforme and chronic lymphocytic leukemia

Cornea. 2007 Oct;26(9):1136-7. doi: 10.1097/ICO.0b013e318123f2c3.

Abstract

Purpose: To describe a patient with a sebaceous adenoma of the bulbar conjunctiva, a distinctly unusual site for this tumor, associated with glioblastoma multiforme and chronic lymphocytic leukemia.

Methods: A 69-year-old woman presented with a red nodule on the temporal bulbar conjunctiva. The mass was excised.

Results: Histopathologic examination of the tumor showed a sebaceous adenoma. Within 3 months, she was discovered to have a temporoparietal glioblastoma multiforme and chronic lymphocytic leukemia. The patient died 5 months after the ocular diagnosis because of cardiovascular complications.

Conclusions: Sebaceous adenoma is an exceedingly rare tumor of the bulbar conjunctiva and may be associated with several systemic malignancies.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma, Sebaceous / pathology*
  • Aged
  • Brain Neoplasms / pathology*
  • Conjunctival Neoplasms / pathology*
  • Fatal Outcome
  • Female
  • Glioblastoma / pathology*
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell / pathology*
  • Neoplasms, Multiple Primary / pathology*