A practical method for 2D multiple-animal MRI

J Magn Reson Imaging. 2007 Oct;26(4):1162-6. doi: 10.1002/jmri.21112.


Purpose: To investigate practical methods for achieving routine simultaneous 2D MRI of multiple animals in large-bore experimental scanners.

Materials and methods: Three four-element array geometries were compared against a standard single-coil configuration in terms of image quality, ease of use, and data efficiency using a four-channel, 4.7 T small animal imaging system.

Results: A linear arrangement of volume resonators permits unobstructed animal preparation and use of an imaging protocol that is almost identical to the single-coil configuration without requiring any image correction or other additional postprocessing. Resulting in vivo images were visually indistinguishable from those acquired through the single-coil configuration.

Conclusion: The efficiency of animal studies employing 2D MRI techniques can be substantially improved by using a linear array of commercially available resonators.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Brain / pathology*
  • Contrast Media / pharmacology
  • Equipment Design
  • Image Processing, Computer-Assisted
  • Magnetic Resonance Imaging / methods*
  • Mice
  • Models, Animal
  • Phantoms, Imaging
  • Reproducibility of Results


  • Contrast Media