Scanning the genome of Mycobacterium tuberculosis to identify potential lectins

Protein Pept Lett. 2007;14(7):683-91. doi: 10.2174/092986607781483813.

Abstract

Lectins are carbohydrate binding proteins with important roles in many biological processes such as adhesion. Here we have identified 11 potential lectins from Mycobacterium tuberculosis H37Rv genome, using a comprehensive bioinformatics analysis, which will provide helpful clues in molecular mapping of pathogenesis and perhaps also serve as potential drug targets.

MeSH terms

  • Amino Acid Sequence
  • Genome, Bacterial*
  • Lectins / chemistry
  • Lectins / genetics*
  • Molecular Sequence Data
  • Mycobacterium tuberculosis / chemistry
  • Mycobacterium tuberculosis / genetics*
  • Protein Structure, Secondary
  • Sequence Homology, Amino Acid

Substances

  • Lectins