The Patient Card questionnaire to identify wearing-off in Parkinson disease

Clin Neuropharmacol. Sep-Oct 2007;30(5):266-75. doi: 10.1097/wnf.0b013e3180413da7.


This study sought to evaluate the feasibility and performance of the Patient Card (PC), an instrument derived from the Patient Questionnaire by Stacy et al, for detection of wearing-off (W-O), in a very first application to a Spanish population with Parkinson disease. Patients were classified as experiencing W-O on the basis of the clinician's Follow-up Questionnaire, the Unified Parkinson Disease Rating Scale-Item 36, or improvement, after the following scheduled dose of medication, of 1 or more symptoms included in the PC. The highest proportion of patients with W-O was identified by the PC (79.8%), followed by the Follow-up Questionnaire (55.4%), and Unified Parkinson Disease Rating Scale (35.1%) (Cochran Q, P < 0.01). The PC Spanish version performed adequately, capturing W-O symptoms more frequently than did the other methods, as in the original Patient Questionnaire study by Stacy et al. Accordingly, the PC may potentially help clinicians identify W-O phenomena and thereby allow for better management of patients with Parkinson disease.

Publication types

  • Evaluation Study
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cognition Disorders / etiology
  • Cross-Sectional Studies
  • Disability Evaluation*
  • Dyskinesia, Drug-Induced
  • Fatigue / etiology
  • Feasibility Studies
  • Female
  • Humans
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care*
  • Parkinson Disease / physiopathology*
  • Severity of Illness Index
  • Spain / epidemiology
  • Surveys and Questionnaires*