Cefuroxime-induced lupus

J Natl Med Assoc. 2007 Sep;99(9):1066-7.


Drug-induced lupus erythematosus (DILE) is a syndrome that shares symptoms and laboratory characteristics with idiopathic systemic lupus erythematosus. Recognition of DILE is important because it usually reverts within a few weeks after stopping the offending drug. Antibiotics are uncommonly associated with DILE, and cefuroxime has never been incriminated as a cause. We present herein the first case of DILE induced by cefuroxime. Although this is the first report of cefuroxime-induced DILE, we should be aware of this occurrence.

Publication types

  • Case Reports

MeSH terms

  • Anti-Bacterial Agents / adverse effects*
  • Cefuroxime / adverse effects*
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / chemically induced*
  • Middle Aged


  • Anti-Bacterial Agents
  • Cefuroxime