Malignant melanoma of the conjunctiva in children: a review of the international literature 1965-2006

J Pediatr Ophthalmol Strabismus. Sep-Oct 2007;44(5):277-82; quiz 298-9. doi: 10.3928/01913913-20070901-01.


Purpose: Conjunctival melanoma is rare in children. This article presents a comprehensive review and discusses the clinical significance of the published cases of malignant melanoma of the conjunctiva in children younger than 15 years.

Materials and methods: To obtain prior reports of conjunctival melanoma in children, a systematic search of the world literature was conducted. Additional studies were identified from the bibliographies of the retrieved articles, as well as from major ophthalmic textbooks.

Results: A review of the literature resulted in 28 reported cases of conjunctival melanoma in children younger than 15 years, and only 8 had adequate case details.

Conclusion: Malignant melanoma of the conjunctiva is a rare condition in children. Limited knowledge for management and prognosis of this condition in children is largely due to its low occurrence.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Conjunctival Neoplasms / pathology*
  • Humans
  • Infant
  • Melanoma / pathology*