Role of ascorbic acid in scavenging free radicals and lead toxicity from biosystems

Mol Biotechnol. 2007 Sep;37(1):62-5. doi: 10.1007/s12033-007-0045-x.


Free radicals are reactive species that are responsible for damaging normal cells and creating diseases in humans. Antioxidants from natural resources or as supplements can scavenge these radicals. A MedLine search indicates that vitamin C is the most investigated antioxidant responsible for the elimination of free radicals. Its chelating property for the removal of neurotoxic lead, which creates oxidative stress in the human biosystem, was investigated and results indicate its great potential as a lead-detoxifying agent.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ascorbic Acid / administration & dosage*
  • Child
  • Female
  • Free Radical Scavengers / administration & dosage*
  • Hair / chemistry*
  • Humans
  • Lead / analysis*
  • Lead / toxicity*
  • Male


  • Free Radical Scavengers
  • Lead
  • Ascorbic Acid