Vitamin D as a novel nontraditional risk factor for mortality in hemodialysis patients: the need for randomized trials

Kidney Int. 2007 Oct;72(8):909-11. doi: 10.1038/


Vitamin D has been used in the context of secondary hyperparathyroidism in patients with end-stage renal disease. A wave of recent studies suggests that vitamin D treatment may be associated with decreased mortality risk in these patients. The article by Wolf et al. further supports these studies by identifying vitamin D deficiency as a risk factor for early mortality in incident hemodialysis patients.

Publication types

  • Comment

MeSH terms

  • Humans
  • Hyperparathyroidism / drug therapy
  • Hyperparathyroidism / etiology
  • Hyperparathyroidism / metabolism
  • Kidney Failure, Chronic / complications*
  • Kidney Failure, Chronic / metabolism*
  • Kidney Failure, Chronic / therapy
  • Randomized Controlled Trials as Topic
  • Renal Dialysis / adverse effects*
  • Risk Factors
  • Survival Analysis
  • Vitamin D / metabolism*
  • Vitamin D / therapeutic use
  • Vitamin D Deficiency / complications*
  • Vitamin D Deficiency / drug therapy
  • Vitamin D Deficiency / metabolism


  • Vitamin D