Guarana (Paullinia cupana var. sorbilis), an anciently consumed stimulant from the Amazon rain forest: the seeded-fruit transcriptome

Plant Cell Rep. 2008 Jan;27(1):117-24. doi: 10.1007/s00299-007-0456-y. Epub 2007 Oct 5.


Guarana (Paullinia cupana var. sorbilis) is a plant native to the central Amazon basin. Roasted seed extracts have been used as medicinal beverages since pre-Colombian times, due to their reputation as stimulants, aphrodisiacs, tonics, as well as protectors of the gastrointestinal tract. Guarana plants are commercially cultivated exclusively in Brazil to supply the national carbonated soft-drink industry and natural product stores around the world. In this report, we describe and discuss the annotation of 15,387 ESTs from guarana seeded-fruits, highlighting sequences from the flavonoid and purine alkaloid pathways, and those related to biotic stress avoidance. This is the largest set of sequences registered for the Sapindaceae family.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Caffeine / metabolism
  • Expressed Sequence Tags
  • Flavonoids / metabolism
  • Fruit / genetics*
  • Fruit / metabolism
  • Gene Expression Profiling / methods*
  • Paullinia / genetics*
  • Paullinia / metabolism
  • Seeds / genetics*
  • Seeds / metabolism
  • Tropical Climate


  • Flavonoids
  • Caffeine