[The clinical study on decompensatory cirrhotic patients treated by Bie Jia Jian]

Zhong Yao Cai. 2007 Jun;30(6):755-7.
[Article in Chinese]

Abstract

Objective: To observe the clinical curative effect on decompensatory cirrhotic patients treated by Bie Jia Jian.

Methods: 98 decompensatory cirrhotic patients were randomly divided into two groups: 49 patients in treatment group and 49 in control group. Both groups were treated with the same western medicine of protecting and supporting liver. Except that, treatment group were treated by Bie Jia Jian.

Results: The Contents of AST, ALT, total bilirubin (TB), direct bilirubin (DB), hyaluronic acid (HA), Laminin (LN) , procollagen III (pc III), and type IV collagen (IV.C) in both groups decreased after treatment, and prothrombin time activity (PTA) increased. Among them, the decrease of TB, DB, HA, LN, PC-III and IV-C, and the increase of PTA in treatment group were more obvious than those in control group (P < 0. 05).

Conclusion: Bie Jia Jian is effective in treating decompesatory cirrhotic patients.

Publication types

  • English Abstract
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alanine Transaminase / blood
  • Aspartate Aminotransferases / blood
  • Biomarkers / blood
  • Collagen Type III / blood
  • Drug Combinations
  • Drugs, Chinese Herbal / administration & dosage
  • Drugs, Chinese Herbal / pharmacology
  • Drugs, Chinese Herbal / therapeutic use*
  • Female
  • Humans
  • Hyaluronic Acid / blood
  • Laminin / blood
  • Liver Cirrhosis / blood
  • Liver Cirrhosis / drug therapy*
  • Liver Function Tests
  • Male
  • Middle Aged
  • Phytotherapy*
  • Treatment Outcome

Substances

  • Biomarkers
  • Collagen Type III
  • Drug Combinations
  • Drugs, Chinese Herbal
  • Laminin
  • bie jia jian
  • Hyaluronic Acid
  • Aspartate Aminotransferases
  • Alanine Transaminase