Diabetic ketoacidosis in pregnancy

Obstet Gynecol Clin North Am. 2007 Sep;34(3):533-43, xii. doi: 10.1016/j.ogc.2007.08.001.


Episodes of diabetic ketoacidosis (DKA) can represent a life-threatening emergency for mother and fetus. The cornerstones of treatment of DKA are aggressive fluid replacement and insulin administration while ascertaining which precipitating factors brought about the current episode of DKA, and then treating accordingly to mitigate those factors. The incidence of DKA and factors unique to pregnancy are discussed in this article, along with the effects of the disease process on pregnancy. Clinical presentation, diagnosis, and treatment modalities are covered in detail to offer ideas to improve maternal and fetal outcome.

Publication types

  • Review

MeSH terms

  • Diabetes, Gestational / diagnosis*
  • Diabetes, Gestational / etiology
  • Diabetes, Gestational / therapy*
  • Diabetic Ketoacidosis / diagnosis*
  • Diabetic Ketoacidosis / etiology
  • Diabetic Ketoacidosis / therapy*
  • Female
  • Humans
  • Pregnancy
  • Pregnancy in Diabetics / diagnosis*
  • Pregnancy in Diabetics / etiology
  • Pregnancy in Diabetics / therapy*