Chemosensory pathways, motility and development in Myxococcus xanthus

Nat Rev Microbiol. 2007 Nov;5(11):862-72. doi: 10.1038/nrmicro1770.


The complex life cycle of Myxococcus xanthus includes predation, swarming, fruiting-body formation and sporulation. The genome of M. xanthus is large and comprises an estimated 7,400 open reading frames, of which approximately 605 code for regulatory genes. These include eight clusters of chemotaxis-like genes that define eight chemosensory pathways, most of which have dedicated functions. Although many of these chemosensory pathways have a role in controlling motility, at least two of these pathways control gene expression during development.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Chemotaxis / genetics
  • Chemotaxis / physiology*
  • Gene Expression Regulation, Bacterial
  • Myxococcus xanthus / genetics
  • Myxococcus xanthus / physiology*