The aging gut: physiology

Clin Geriatr Med. 2007 Nov;23(4):757-67, v-vi. doi: 10.1016/j.cger.2007.06.002.


Changes in the physiology of the gastrointestinal tract with aging are less obvious than are seen in other organs, such as the brain. Nevertheless, physiologic changes play a role in the anorexia of aging, postprandial hypotension, aspiration pneumonia, increased Clostridium difficile infections, fecal incontinence, gallstones, and altered drug metabolism.

Publication types

  • Review

MeSH terms

  • Aging / physiology*
  • Anorexia / etiology
  • Anorexia / physiopathology
  • Blood Pressure / physiology
  • Gastrointestinal Motility / physiology
  • Gastrointestinal Tract / physiopathology*
  • Humans
  • Intestinal Absorption / physiology
  • Postprandial Period / physiology