Desquamative interstitial pneumonitis causing acute respiratory failure, responsive only to immunosuppressants

Respiration. 1991;58(5-6):324-6. doi: 10.1159/000195954.


We present a case of a 66-year-old man who suffered from acute respiratory failure due to desquamative interstitial pneumonia. The pneumonitis was resistant to steroids, but responded promptly to cyclophosphamide, with immediate relapse upon withdrawal of the drug.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Aged
  • Cyclophosphamide / administration & dosage
  • Cyclophosphamide / therapeutic use*
  • Humans
  • Male
  • Pulmonary Fibrosis / complications*
  • Pulmonary Fibrosis / drug therapy
  • Respiratory Insufficiency / drug therapy
  • Respiratory Insufficiency / etiology*


  • Cyclophosphamide