Hedgehog signaling pathway
- PMID: 17925577
- DOI: 10.1126/stke.4072007cm6
Hedgehog signaling pathway
Abstract
The Hedgehog (Hh) signaling pathway is essential for development and tissue homeostasis in metazoans. Probably as a result of its potent influence on cell-fate outcomes, the Hh pathway when corrupted results in malformations and diseases such as cancer. Many of the pathway components that contribute to Hh-mediated signal transduction are presented.
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