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Review
. 2007 Oct 9;2007(407):cm6.
doi: 10.1126/stke.4072007cm6.

Hedgehog signaling pathway

Affiliations
Review

Hedgehog signaling pathway

Leni Jacob et al. Sci STKE. .

Abstract

The Hedgehog (Hh) signaling pathway is essential for development and tissue homeostasis in metazoans. Probably as a result of its potent influence on cell-fate outcomes, the Hh pathway when corrupted results in malformations and diseases such as cancer. Many of the pathway components that contribute to Hh-mediated signal transduction are presented.

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