[Diagnosis and treatment using double balloon endoscopy]

Nihon Rinsho. 2007 Oct;65(10):1866-74.
[Article in Japanese]


Double balloon endoscopy (DBE) and video capsule endoscopy (VCE) are breakthrough methods for endoscopic examination of the small intestine. Using these modalities, it has been clarified that use of nonsteroidal anti-inflammatory drugs (NSAIDs) induces ulcers not only in upper gastrointestinal tract but also in the small intestine. Furthermore, concentric membranous strictures, so called "diaphragm disease" can be induced with long-term NSAID use in some cases. The best therapy for ulcers induced by NSAIDs in small intestine is cessation of NSAIDs use so far. For these diaphragm-like small intestinal strictures, a balloon dilation therapy using DBE can be performed safety and effectively.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Aged
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
  • Endoscopy, Gastrointestinal / methods*
  • Female
  • Humans
  • Intestinal Diseases / chemically induced*
  • Intestinal Diseases / drug therapy
  • Intestinal Diseases / pathology*
  • Intestine, Small
  • Middle Aged
  • Ulcer / chemically induced
  • Ulcer / drug therapy
  • Ulcer / pathology


  • Anti-Inflammatory Agents, Non-Steroidal