Hyperpolarized (89)Y offers the potential of direct imaging of metal ions in biological systems by magnetic resonance

J Am Chem Soc. 2007 Oct 31;129(43):12942-3. doi: 10.1021/ja075768z. Epub 2007 Oct 10.


Hyperpolarization of 89YCl3 and three 89Y-complexes was achieved by dynamic nuclear polarization of aqueous samples. The long T1’s of 89Y make its application as an MR imaging probe extremely promising. In addition, the wide chemical shift range for various chelates of 89Y means that agents sensitive to their biological/chemical milieu could serve as exquisite sensors of important biological events.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biology
  • Ions / chemistry
  • Magnetic Resonance Spectroscopy / methods*
  • Yttrium / chemistry*


  • Ions
  • Yttrium