A transient ischaemic attack clinic with round-the-clock access (SOS-TIA): feasibility and effects

Lancet Neurol. 2007 Nov;6(11):953-60. doi: 10.1016/S1474-4422(07)70248-X.


Background: Diagnosis and treatment of cerebral and retinal transient ischaemic attacks (TIAs) are often delayed by the lack of immediate access to a dedicated TIA clinic. We evaluated the effects of rapid assessment of patients with TIA on clinical decision making, length of hospital stay, and subsequent stroke rates.

Methods: We set up SOS-TIA, a hospital clinic with 24-h access. Patients were admitted if they had sudden retinal or cerebral focal symptoms judged to relate to ischaemia and if they made a total recovery. Assessment, which included neurological, arterial, and cardiac imaging, was within 4 h of admission. A leaflet about TIA with a toll-free telephone number for SOS-TIA was sent to 15 000 family doctors, cardiologists, neurologists, and ophthalmologists in Paris and its administrative region. Endpoints were stroke within 90 days, and stroke, myocardial infarction, and vascular death within 1 year.

Findings: Between January, 2003, and December, 2005, we admitted 1085 patients with suspected TIA; 574 (53%) were seen within 24 h of symptom onset. 701 (65%) patients had confirmed TIA or minor stroke, and 144 (13%) had possible TIA. 108 (17%) of the 643 patients with confirmed TIA had brain tissue damage. Median duration of symptoms was 15 min (IQR 5-75 min). Of the patients with confirmed or possible TIA, all started a stroke prevention programme, 43 (5%) had urgent carotid revascularisation, and 44 (5%) were treated for atrial fibrillation with anticoagulants. 808 (74%) of all patients seen were sent home on the same day. The 90-day stroke rate was 1.24% (95% CI 0.72-2.12), whereas the rate predicted from ABCD(2) scores was 5.96%.

Interpretation: Use of TIA clinics with 24-h access and immediate initiation of preventive treatment might greatly reduce length of hospital stay and risk of stroke compared with expected risk.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anticoagulants / therapeutic use
  • Atrial Fibrillation / complications
  • Atrial Fibrillation / drug therapy
  • Brain / diagnostic imaging
  • Brain / pathology
  • Carotid Artery Diseases / complications
  • Carotid Artery Diseases / surgery
  • Cerebral Revascularization
  • Circadian Rhythm*
  • Emergency Medical Services*
  • Feasibility Studies
  • Humans
  • Incidence
  • Ischemic Attack, Transient / complications
  • Ischemic Attack, Transient / diagnosis*
  • Ischemic Attack, Transient / etiology
  • Ischemic Attack, Transient / therapy*
  • Magnetic Resonance Imaging
  • Neurology*
  • Outpatient Clinics, Hospital*
  • Stroke / epidemiology
  • Stroke / etiology
  • Stroke / prevention & control*
  • Time Factors
  • Tomography, X-Ray Computed


  • Anticoagulants