Evaluation of lumbar bone mineral density by dual energy x-ray absorptiometry

Acta Paediatr Jpn. 1991 Aug;33(4):459-66. doi: 10.1111/j.1442-200x.1991.tb02572.x.


Using dual-energy x-ray absorptiometry (DEXA), the lumbar spinal bone mineral density (BMD) in 49 Japanese children with or without metabolic bone disease (MBD) was determined. The following results were obtained: (a) The normal data for healthy Caucasians (J Clin Endocrinol Metab 1990; 70: 1330-1333) appear to be applicable to Japanese children; (b) BMD was normal in patients with congenital hydronephrosis with normal renal function; (c) One patient with congenital renal failure and one with Lowe syndrome had low BMD, but the MBD in the former improved markedly with peritoneal dialysis; (d) A reduced BMD was found in patients treated with long-term steroids, probably because of decreased turnover of bone; (e) A reduction in BMD was pronounced in preterm infants during the first few months of life. In conclusion, DEXA is a useful method of bone densitometry in MBD in children.

MeSH terms

  • Absorptiometry, Photon*
  • Adolescent
  • Asian Continental Ancestry Group
  • Bone Density*
  • Bone Diseases, Metabolic / diagnostic imaging*
  • Bone Diseases, Metabolic / physiopathology
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Premature
  • Japan
  • Lumbar Vertebrae / diagnostic imaging*
  • Male
  • Osteoporosis / chemically induced
  • Osteoporosis / diagnostic imaging
  • Reference Values
  • Steroids / adverse effects


  • Steroids