Identification of a Malate Chemoreceptor in Pseudomonas Aeruginosa by Screening for Chemotaxis Defects in an Energy Taxis-Deficient Mutant

Appl Environ Microbiol. 2007 Dec;73(23):7793-5. doi: 10.1128/AEM.01898-07. Epub 2007 Oct 12.

Abstract

We found that a robust energy taxis response mediated by the Aer receptor can sometimes mask chemotaxis mediated by other methyl-accepting chemotaxis proteins (MCPs) in Pseudomonas aeruginosa. We identified PA2652 as a chemoreceptor for malate by screening aer mcp double mutants by using swarm plate assays.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Bacterial Proteins / physiology
  • Chemoreceptor Cells / metabolism*
  • Chemotaxis / genetics
  • Chemotaxis / physiology*
  • Malates / metabolism*
  • Membrane Proteins / genetics
  • Membrane Proteins / metabolism
  • Membrane Proteins / physiology
  • Methyl-Accepting Chemotaxis Proteins
  • Mutation*
  • Pseudomonas aeruginosa / genetics*
  • Pseudomonas aeruginosa / metabolism
  • Pseudomonas aeruginosa / physiology

Substances

  • Bacterial Proteins
  • Malates
  • Membrane Proteins
  • Methyl-Accepting Chemotaxis Proteins
  • malic acid