Twenty Years of PSA: From Prostate Antigen to Tumor Marker

Rev Urol. 2007 Summer;9(3):113-23.

Abstract

The measurement of prostate-specific antigen in serum is credited with dramatic advances in the early detection of men with prostatic carcinoma. This report summarizes the history of biochemical research and the current understanding and application of prostate-specific antigen in prostate cancer diagnostics.

Keywords: Human kallikrein; Immunoassays; Prostate cancer; Prostate-specific antigen.