We report a personal case of myocardial infarction with flurbiprofen used instead of clopidogrel before an operation. We re-examined the literature concerning the management of the antiagregant treatment of the patient with angioplasty and/or stent who needs surgery. This management proves to be delicate and all the questions that it raises have not so far been answered in particular with regard to the problem of resistance to aspirin. Anyway this personal observation supports our view that contrary to certain recomendations flurbiprofène is not a satisfactory alternative to aspirin either with or without thiénopyridine.