Acute 'upside-down' visual inversion due to multiple sclerosis

Mult Scler. 2008 Mar;14(2):266-7. doi: 10.1177/1352458507082045. Epub 2007 Oct 17.


In a 20-year-old male patient, a 180 degree inversion of visual image was found as a manifestation of multiple sclerosis. Upside down reversal of vision is not a well-known sign in multiple sclerosis. Exact mechanism is still unknown. Lesions involving cortical areas, mainly the parieto-occipital region, have occasionally been documented. To our knowledge this is the first report of upside-down reversal of vision in multiple sclerosis with cerebra lesion on MRI.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cerebellar Diseases / etiology*
  • Cerebellar Diseases / pathology
  • Cerebellum / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Multiple Sclerosis / complications*
  • Multiple Sclerosis / pathology
  • Perceptual Distortion*
  • Vision Disorders / etiology*
  • Vision Disorders / pathology