Right ventricular thrombus with Behçet's syndrome: successful treatment with warfarin and immunosuppressive agents

Tex Heart Inst J. 2007;34(3):360-2.

Abstract

Behçet's syndrome is a chronic multisystem disease that presents with recurrent oral and genital ulceration and recurrent uveitis. Cardiac involvement is an extremely rare manifestation of this disorder. A 33-year-old man with Behçet's syndrome was admitted to our department with a history of cough, fever, chest pain, hemoptysis, and weight loss. Transthoracic and transesophageal echocardiography revealed a right ventricular thrombus. After 1 month of treatment with warfarin, cyclophosphamide, and corticosteroid, the intracardiac thrombus resolved.

Keywords: Behcet's syndrome/complications/drug therapy; Mediterranean region/epidemiology; Middle East/epidemiology; diagnosis, differential; echocardiography, transesophageal; heart ventricles/ultrasonography; immunosuppressive agents/therapeutic use; thrombosis/etiology; vasculitis; warfarin/therapeutic use.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anticoagulants / therapeutic use
  • Behcet Syndrome / complications*
  • Behcet Syndrome / diagnosis*
  • Behcet Syndrome / epidemiology
  • Cyclophosphamide / therapeutic use
  • Drug Therapy, Combination
  • Glucocorticoids / therapeutic use
  • Heart Diseases / diagnostic imaging
  • Heart Diseases / drug therapy
  • Heart Diseases / epidemiology
  • Heart Diseases / etiology*
  • Heart Ventricles*
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Methylprednisolone / therapeutic use
  • Pulmonary Embolism / epidemiology
  • Recurrence
  • Thrombophlebitis / epidemiology
  • Thrombosis / diagnostic imaging
  • Thrombosis / drug therapy
  • Thrombosis / epidemiology
  • Thrombosis / etiology*
  • Ultrasonography
  • Warfarin / therapeutic use

Substances

  • Anticoagulants
  • Glucocorticoids
  • Immunosuppressive Agents
  • Warfarin
  • Cyclophosphamide
  • Methylprednisolone